Details for gene set NCI_IL2-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos
Phenotype	phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	NCI_IL2-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.6131057
Normalized Enrichment Score (NES)	-1.5425882
Nominal p-value	0.0
FDR q-value	0.33624274
FWER p-Value	0.939

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RPS6	2060168	478	1.354	0.0014	No
2	MAPKAPK2	2850500	572	1.240	0.0213	No
3	IL2RA	6620450	647	1.126	0.0399	No
4	STAT5A	2680458	724	1.049	0.0568	No
5	JAK3	70347 3290008	985	0.859	0.0600	No
6	SOCS3	5550563	1234	0.696	0.0606	No
7	ARRB2	2060441	1293	0.658	0.0707	No
8	E2F1	5360093	1330	0.638	0.0816	No
9	HRAS	1980551	1508	0.558	0.0832	No
10	MAPK3	580161 4780035	1667	0.499	0.0847	No
11	PRKCZ	3780279	1695	0.488	0.0930	No
12	NFKB1	5420358	1928	0.422	0.0890	No
13	GRB2	6650398	2319	0.313	0.0742	No
14	PRF1	6660309	2711	0.213	0.0573	No
15	IL2RB	4730072	2982	0.168	0.0461	No
16	BCL3	3990440	3203	0.139	0.0370	No
17	PPP2R5D	4010156 380408 5550112 5670162	3414	0.116	0.0280	No
18	MAP2K2	4590601	3424	0.115	0.0298	No
19	SMPD1	1410309 5550717	3437	0.114	0.0315	No
20	PRKCA	6400551	3576	0.103	0.0261	No
21	NRAS	6900577	4430	0.057	-0.0189	No
22	RPS6KB1	1450427 5080110 6200563	4932	0.043	-0.0451	No
23	HSP90AA1	4560041 5220133 2120722	4987	0.042	-0.0472	No
24	IL4	6020537	5032	0.041	-0.0487	No
25	FRAP1	2850037 6660010	5731	0.028	-0.0859	No
26	CALM1	380128	6258	0.021	-0.1139	No
27	CDK6	4920253	6691	0.017	-0.1369	No
28	PIK3R1	4730671	7321	0.013	-0.1706	No
29	FOS	1850315	7390	0.012	-0.1741	No
30	SOS1	7050338	7726	0.010	-0.1920	No
31	PTPN11	2230100 2470180 6100528	8524	0.007	-0.2349	No
32	REL	360707	8673	0.007	-0.2428	No
33	AKT1	5290746	9329	0.005	-0.2781	No
34	RAN	2260446 4590647	9367	0.004	-0.2800	No
35	XPO1	540707	9449	0.004	-0.2843	No
36	IL2	1770725	9837	0.003	-0.3051	No
37	GAB2	1410280 2340520 4280040	10137	0.002	-0.3212	No
38	PRKCE	5700053	10501	0.001	-0.3408	No
39	INSL3	4150092	10652	0.001	-0.3489	No
40	MYC	380541 4670170	10764	0.000	-0.3549	No
41	SGMS1	4780195	10842	0.000	-0.3591	No
42	ATM	3610110 4050524	10891	0.000	-0.3616	No
43	TNF	6650603	12391	-0.005	-0.4426	No
44	TERT	6660075	12800	-0.007	-0.4645	No
45	IFNG	5670592	12891	-0.007	-0.4692	No
46	FBXW11	6450632	13100	-0.009	-0.4802	No
47	SRC	580132	13235	-0.010	-0.4873	No
48	IRS1	1190204	13369	-0.011	-0.4943	No
49	SYK	6940133	13689	-0.014	-0.5112	No
50	FOXO3	2510484 4480451	13812	-0.016	-0.5175	No
51	JUN	840170	13846	-0.016	-0.5189	No
52	PIK3CA	6220129	13861	-0.016	-0.5194	No
53	STAT5B	6200026	13947	-0.018	-0.5236	No
54	ERC1	1580170 2630717 6110762 6840280	14397	-0.028	-0.5473	No
55	CCNA2	5290075	14835	-0.048	-0.5699	No
56	NOD2	2510050	14872	-0.050	-0.5709	No
57	STAM	3850008 4760441	14899	-0.052	-0.5712	No
58	MALT1	4670292	14919	-0.053	-0.5712	No
59	STAM2	730731 2120377	14969	-0.055	-0.5727	No
60	MAPK11	130452 3120440 3610465	15150	-0.068	-0.5811	No
61	FASLG	2810044	15163	-0.069	-0.5804	No
62	RELB	1400048	15248	-0.075	-0.5834	No
63	LTA	1740088	15289	-0.079	-0.5840	No
64	SHC1	2900731 3170504 6520537	15309	-0.081	-0.5834	No
65	IKBKG	3450092 3840377 6590592	15397	-0.091	-0.5863	No
66	JAK1	5910746	15408	-0.091	-0.5850	No
67	BIRC2	2940435 4730020	15427	-0.093	-0.5841	No
68	MAP2K1	840739	15475	-0.098	-0.5847	No
69	NFKB2	2320670	15588	-0.110	-0.5885	No
70	FYN	2100468 4760520 4850687	15761	-0.130	-0.5952	No
71	UBE2D3	3190452	15912	-0.149	-0.6003	No
72	MAPK1	3190193 6200253	15968	-0.160	-0.6001	No
73	BCL2	730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164	15995	-0.163	-0.5982	No
74	RAC1	4810687	16093	-0.176	-0.5999	No
75	RIPK2	5050072 6290632	16153	-0.187	-0.5993	No
76	DOK2	5340273	16176	-0.191	-0.5966	No
77	FOXP3	940707 1850692	16316	-0.219	-0.5998	No
78	MAPK8	2640195	16564	-0.281	-0.6075	Yes
79	IKBKB	6840072	16617	-0.298	-0.6043	Yes
80	LCK	3360142	16671	-0.311	-0.6009	Yes
81	CALM2	6620463	16731	-0.330	-0.5975	Yes
82	SP1	6590017	16789	-0.347	-0.5936	Yes
83	CDK2	130484 2260301 4010088 5050110	16829	-0.357	-0.5885	Yes
84	RELA	3830075	16834	-0.358	-0.5815	Yes
85	RAF1	1770600	16929	-0.388	-0.5788	Yes
86	CYLD	6590079	17073	-0.438	-0.5777	Yes
87	KRAS	2060170	17160	-0.476	-0.5728	Yes
88	MYB	1660494 5860451 6130706	17283	-0.524	-0.5689	Yes
89	CALM3	3390288	17358	-0.561	-0.5616	Yes
90	CHUK	7050736	17374	-0.567	-0.5510	Yes
91	TRAF6	4810292 6200132	17407	-0.581	-0.5411	Yes
92	MAPK14	5290731	17410	-0.583	-0.5295	Yes
93	NFKBIA	1570152	17455	-0.610	-0.5196	Yes
94	SOCS2	4760692	17482	-0.624	-0.5085	Yes
95	RASA1	1240315	17696	-0.741	-0.5051	Yes
96	BCL10	2360397	17734	-0.764	-0.4918	Yes
97	MAP3K14	5890435	17867	-0.866	-0.4815	Yes
98	SOCS1	730139	17976	-0.958	-0.4681	Yes
99	IL2RG	4120273	17992	-0.973	-0.4494	Yes
100	STAT1	6510204 6590553	18024	-1.010	-0.4308	Yes
101	STAT3	460040 3710341	18039	-1.029	-0.4109	Yes
102	PTK2B	4730411	18075	-1.069	-0.3913	Yes
103	BCL2L1	1580452 4200152 5420484	18144	-1.180	-0.3713	Yes
104	ELF1	4780450	18178	-1.217	-0.3486	Yes
105	UGCG	3420053	18307	-1.492	-0.3255	Yes
106	MAPK9	2060273 3780209 4070397	18410	-1.795	-0.2950	Yes
107	TNFAIP3	2900142	18460	-1.987	-0.2578	Yes
108	CISH	840315	18478	-2.069	-0.2171	Yes
109	CCND3	380528 730500	18479	-2.071	-0.1755	Yes
110	RHOA	580142 5900131 5340450	18507	-2.308	-0.1306	Yes
111	CCND2	5340167	18568	-2.711	-0.0794	Yes
112	TNFRSF1A	1090390 6520735	18609	-4.080	0.0004	Yes